The effects of Psilocybin mushrooms come from psilocybin and psilocin. They do create short-term increases in tolerance of users, thus making it difficult to abuse them because the more often they are taken within a short period of time, the weaker the resultant effects are. When psilocybin is ingested, it is broken down to produce psilocin, which is responsible for the hallucinogenic effects.As with many psychedelic substances, the effects of psychedelic mushrooms are subjective and can vary considerably among individual users. The mind-altering effects of psilocybin-containing mushrooms typically last anywhere from 3 to 8 hours depending on dosage, preparation method, and personal metabolism. However, the effects can seem to last much longer because of psilocybin\’s ability to alter time perception.